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egoroff_w [7]
3 years ago
9

Mutations in genes encoding cell signaling proteins contribute to many cancers. For example, a chromosomal translocation fuses t

he Bcr gene to the Abl gene, leading to a constitutively active Bcr–Abl kinase and chronic myeloid leukemia (CML). CML is successfully treated with the drug imatinib (trade name Gleevec), which mimics an Abl kinase substrate and thus inhibits kinase activity. What normal cell molecule, and kinase substrate, does Gleevec mimic?
Chemistry
1 answer:
schepotkina [342]3 years ago
6 0

Imatinib is a small molecule kinase inhibitor. The BCR-ABL kinase can phosphorylate a series of downstream substrates, leading to proliferation of mature granulocytes. Bcr-Abl kinase substrate is the tyrosine. The Protein Tyrosine Kinase activity is an important requirement for malignant transformation, and that it cannot be complemented by any downstream effector, though not all interactions of BCR-ABL with other proteins are phosphotyrosine dependent.

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What is the mass of solute in a 500 mL solution of 0.200 M
Fofino [41]

16.4 grams is the mass of solute in a 500 mL solution of 0.200 M .

sodium phosphate

Explanation:

Given data about sodium phosphate

atomic mass of Na3PO4 = 164 grams/mole

volume of the solution = 500 ml or 0.5 litres

molarity of sodium phosphate solution = 0.200 M

The formula for molarity will be used here to know the mass dissolved in the given volume of the solution:

The formula is

molarity = \frac{number of moles of solute}{volume in litres}

    putting the values in the equation, we get

molarity x volume = number of moles

0.200 X 0.5= number of  moles

number of moles = 0.1 moles

Atomic mass x number of moles = mass

putting the values in the above equation

164 x 0.1 = 16.4 grams

16.4 grams of sodium phosphate is present in 0.5 L of the solution to make a 0.2 M solution.

8 0
3 years ago
Do electrons have more or less mass than neutrons
nata0808 [166]
Electrons have less mass than a neutron.
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3 years ago
Brainliest for an answer!
Degger [83]

The volume of H₂ : = 15.2208 L

<h3>Further explanation</h3>

Given

Reaction

2 As (s) + 6 NaOH (aq) → 2 Na₃AsO₃ (s) + 3 H₂ (g)

34.0g of As

Required

The volume of H₂ at STP

Solution

mol As (Ar = 75 g/mol) :

= mass : Ar

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A single atom of an element has 21 nutrons 20 electtons and 20 protons which element is it
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