An acetic acid buffer solution is required to have a pH of 5.27. You have a solution that contains 0.01 mol of acetic acid. What
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Answer:
D. Anti-periplanar
Explanation:
In the <u>second step</u> of the intramolecular William Ether Synthesis mechanism (figure 1) we will have the attack of the negative charge of the oxygen to the carbon bond to the Br. At the same time the Br leaves, so a bond would be broken (the <u>C-Br</u> bond) and a bond would be formed (the <u>C-O</u> bond).
Now, this process can happen only if the <u>attack</u> and the <u>leaving group </u>has an anti configuration (figure 2). In an anti configuration the <u>nucleophile</u> and the <u>leaving group</u> would have <u>opposite directions</u>.
