Question

t the R group in the reagent over the arrow be isopropyl. (i.e. The reagent is LiN[CH(CH3)2]2.) Now, fill in the blanks. This reaction will follow ______ rule and will form the _________ substituted alkene. a. Zaitzev's; more b. Zaitzev's; less c. Hofmann's; less d. Hofmann's; more

Answer 1

Answer:. A

Explanation:

T the R group in the reagent over the arrow be isopropyl. (i.e. The reagent is LiN[CH(CH3)2]2.) Now, fill in the blanks. This reaction will follow Zaitzev'srule and will form the more substituted alkene.

Answer 2

Answer:c. Hofmann's; less

Explanation:

The Hofmann elimination process, named after its discoverer, the German chemist August Wilhelm Von Hofmann rule states that the major alkene product is the least substituted and least stable product when it comes to asymmetrical amines.  The Hofmann elimination can be illustrated in t e formation of “Hoffman” products in elimination reactions  using a less common, LDA LiN[CH(CH3)2]2  Lithium Di-isopropyl Amide (LDA) usually with base  potassium t-butoxide  which will give rise to a less substituted alkene.

This reaction will follow Hofmann's_____ rule and will form the ___less______ substituted alkene.