For multiple covalent bonds to form in molecules, the molecules must contain carbon nitrogen or oxygen.
<u>Explanation:</u>
- Think about carbon dioxide (CO2). If every oxygen atom imparts one electron to the carbon molecule, there will be 6 electrons in carbon particle and 7 electrons in every oxygen atom. This doesn't give the carbon atom as a total octet.
- Sometimes more than one set of electrons is shared between two atoms. In carbon dioxide, a second electron from every oxygen atom is likewise imparted with the central carbon atom, and the carbon particle imparts one more electron with every oxygen atom.
- Two sets of electrons shared between two atoms make a double bond between the atoms. A few particles contain triple bonds, covalent bonds in which three sets of electrons are shared by two atoms.
Imatinib is a small molecule kinase inhibitor. The BCR-ABL kinase can phosphorylate a series of downstream substrates, leading to proliferation of mature granulocytes. Bcr-Abl kinase substrate is the tyrosine. The Protein Tyrosine Kinase activity is an important requirement for malignant transformation, and that it cannot be complemented by any downstream effector, though not all interactions of BCR-ABL with other proteins are phosphotyrosine dependent.
If Ka for HCN is 6. 2×10^−10 at 25 °C, then the value of Kb for cn− at 25 °C is 1.6 × 10^(-5).
<h3>What is base dissociation constant? </h3><h3 />
The base dissociation constant (Kb) is defined as the measurement of the ions which base can dissociate or dissolve in the aqueous solution. The greater the value of base dissociation constant greater will be its basicity an strength.
The dissociation reaction of hydrogen cyanide can be given as
HCN --- (H+) + (CN-)
Given,
The value of Ka for HCN is 6.2× 10^(-10)
The correlation between base dissociation constant and acid dissociation constant is
Kw = Ka × Kb
Kw = 10^(-14)
Substituting values of Ka and Kw,
Kb = 10^(-14) /{6.2×10^(-10) }
= 1.6× 10^(-5)
Thus, the value of base dissociation constant at 25°C is 1.6 × 10^(-5).
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Explanation: Groundwater can cause erosion under the surface as it moves through the soil. During the movement an acid is formed which what causes erosion and deposition.
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