Ibuprofen is synthesized by reacting ethyl 2-(4-isobutylphenyl)acetate with base, the base abstracts the acidic proton and enolate is formed which on reaction with diethyl carbonate generates diethyl 2-(4-isobutylphenyl)malonate
(A). diethyl 2-(4-isobutylphenyl)malonate on treatment with Base again looses the acidic proton and forms enolate. The enolate with treatment with Methyl Iodide yields diethyl 2-(4-isobutylphenyl)-2-methylmalonate
(B). diethyl 2-(4-isobutylphenyl)-2-methylmalonate on
hydrolysis give
Ibuprofen.
a. 35.8 KJ
b. 871 g
c. Fe
..........................................................................................
Answer:
1 : 2
Explanation:
From the question given, we obtained the following information:
T1 = 287°C = 287 +273 = 560K
T1 = 587°C = 587 +273 =860K
V1 = V
V2 =?
V1 /T1 = V2 /T2
V/560 = V2/860
Cross multiply
V2 x 560 = 860 x V
Divide both side by 560
V2 = (860 x V) / 560
V2 = 1.54V = 2V
The ratio of initial to final volume =
V1 : V2
= V : 2V
= 1 : 2