Cyclic nucleotides cAMP and cGMP are part of almost all major cellular signaling pathways. Phosphodiesterases (PDEs) are enzymes that regulate the intracellular levels of cAMP and cGMP. Protein kinase A or cAMP-dependent protein kinase mediates most cAMP effects in the cell. Over the last 25 years, various components of this group of molecules have been involved in human diseases, both genetic and acquired. Lately, the PDEs attract more attention. The pharmacological exploitation of the PDE’s ability to regulate cGMP and cAMP, and through them, a variety of signaling pathways, has led to a number of new drugs for diverse applications from the treatment of erectile dysfunction to heart failure, asthma, and chronic obstructive pulmonary disease. We present the abstracts (available online) and selected articles from the proceedings of a meeting that took place at the National Institutes of Health (NIH), Bethesda, MD, June 8–10, 2011.
Answer:
Frequency = 1.25 ×10¹³ Hz
Explanation:
Given data:
Wavelength of light = 24.0 μm (2.4 ×10⁻⁵ m)
Frequency = ?
Solution:
Formula:
Speed of light = wavelength × frequency
Speed of light /wavelength = frequency
Frequency = 3×10⁸ m /s /2.4 ×10⁻⁵m
Frequency = 1.25 ×10¹³ s⁻¹
s⁻¹ = Hz
Frequency = 1.25 ×10¹³ Hz
The Embargo Act of 1807 and the Neutrality Acts of the 1930's were both attempts by the United States to avoid foreign conflicts. The correct option in regards to all the options given in the question is option "3".
The Embargo Act of 1807
prohibited all kinds of exports from United states of America. This Act would
treat any export as illegal. This Act was also intended to keep America from
avoiding any conflicts with the warring nations. The Neutrality act was also
intended towards remaining neutral towards all fighting nations.
Answer:
Number of moles = 558.46 mol
Explanation:
Density = 804 g/L
Molecular formula = C13H28
Molar mass = 184.37 g/mol
Distance = 3680 km
Rate = 3.48 L of fuel per 100. km
Volume is calculated as follow;
3.48 = 100
x = 3680
x = 3680 * 3.48 / 100
x = 128.064 L
Number of moles = Mass / Molar mass
Mass = Density * Volume
Mass = 804 * 128.064 = 102963.456 g
Number of moles = 102963.456 / 184.37
Number of moles = 558.46 mol
