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mixas84 [53]
3 years ago
13

Why chemically did the prescribing of thalidomide for morning sickness in pregnant women lead to tragic consequences, including

teratogenic effects?
Chemistry
1 answer:
Dominik [7]3 years ago
3 0

Answer:

See explanation

Explanation:

The drug thalidomide with molecular formula C13H10N2O4 was widely prescribed by doctors for morning sickness in pregnant women in the 1960s.

The drug was sold as a racemic mixture  (+)(R)-thalidomide and (-)(S)-thalidomide.

Unfortunately, only the  (+)(R)-thalidomide exhibited the required effect while (-)(S)-thalidomide is a teratogen.

This goes a long way to underscore the importance of separation of enantiomers in drug production.

Therefore, all the teratogenic effects observed when using the drug thalidomide was actually as a result of the presence of (-)(S)-thalidomide, the unwanted enantiomer.

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Cho 4g CuO vào dung dịch axit clohidric 10% thì phản ứng vừa đủ.
Sholpan [36]

Answer:

Explanation:

a. CuO+ 2HCl⇒CuCl2+ H2O

b. n_{CuO}= \frac{4}{80}= 0,05 (mol)

⇒n_{CuCl2}= n_{CuO}=0,05 mol

⇒m_{CuCl2}= 0,05×135=6,75 (g)

c. n_{HCl}=2× n_{CuO}=0,1 (mol)

⇒m_{HCl}= 0,1×36,5= 3,65 (g)

⇒m_{dd HCl}= \frac{m_{HCl}}{10}×100=36,5 (g)

⇒ Nồng độ phần trăm dd sau phản ứng= Nồng độ % dd CuCl2=\frac{m_{CuCl2} }{m_{dd HCl+ m_{CuO} } }×100=\frac{6,75}{36,5+4} ×100≈ 16,67%

8 0
3 years ago
1 Copy and complete using the words below:
Aleks [24]

Answer:

The elements in__Group_ 0 of the Periodic Table are called the_noble__gases. They are generally __unreactive_. because they have a__full_outer shell of electrons. So they do not need to gain__lose_or share _electrons_ with other atoms.

5 0
4 years ago
Identify the solute and solvent in a solution made from 15 mL of oxygen and 5 mL of helium.
Marina CMI [18]

Answer:

Oxygen is solvent and Helium is solute.

Explanation:

Helium is a complety inert gas which do not react with other compounds whereas, oxygen can take part in chemical reaction with many compounds.

  • if we mix 15 mL of oxygen and 5mL of helium then the oxygen is the solvent and helium is solute.
  • In a mixture the compound with the greater volume is solvent and the compound with lwss volume is solute.
  • in this case, oxygen has greater volume than that of helium so oxygen is solute and helium is solvent here.
6 0
3 years ago
Complete and balance the equations for the given single displacement reactions. Write the reaction in molecular form. Phases are
Elan Coil [88]

Answer:

Li(s) + H2O(l) -----> LiOH(aq) + H2(g)

Ca(s) + 2H2O(l) ---------------> Ca(OH)2(aq) + H2(g)

Explanation:

Metals react with water to yield the metal hydroxide and hydrogen gas as shown in the answer above.

The reaction equations were balanced, the number of atoms of each element on both side of the reaction equation is exactly the same.

This is the way to write a balanced reaction equation for the species shown in the question.

5 0
3 years ago
What is the empirical formula of a compound containing 5.03 grams carbon, 0.42 grams hydrogen, and 44.5 grams chlorine?
PtichkaEL [24]

Answer:

The right choice is CHCl₃

Explanation:

  • <u>To find the empirical formula firstly, change the mass to moles.</u>

For Carbon :

no. of moles = (mass / molar mass) = (5.03 g / 12  g/mol )=  0.42 mol

<u><em>For Hydrogen  :</em></u>

no. of moles = (mass / molar mass) = (0.42 g / 1  g/mol )=  0.42 mol

<u><em>For Chlorine :</em></u>

no. of moles = (mass / molar mass) = (44.5 g / 35.5 g/mol )=  1.25 mol

The ratio for Carbon and Hydrogen is  1 : 1

0.42 mol / 042 mol =1.00

  • <u> Then find a ratio between the moles. </u>

The ratio of Chlorine to both Carbon and Hydrogen is 3:1

1.25 mol / 0.42 mol = 2.98 ≅ 3

So the ratio is 1 C : 1 H : 3 Cl.

So, the right choice is CHCl₃

Carbon usually forms four bonds one to Hydrogen and 3 to Chlorine atoms.

Chlorine usually forms one bond to Carbon atom.

Hydrogen usually forms one bond Carbon atom.

4 0
3 years ago
Read 2 more answers
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