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mixas84 [53]
3 years ago
13

Why chemically did the prescribing of thalidomide for morning sickness in pregnant women lead to tragic consequences, including

teratogenic effects?
Chemistry
1 answer:
Dominik [7]3 years ago
3 0

Answer:

See explanation

Explanation:

The drug thalidomide with molecular formula C13H10N2O4 was widely prescribed by doctors for morning sickness in pregnant women in the 1960s.

The drug was sold as a racemic mixture  (+)(R)-thalidomide and (-)(S)-thalidomide.

Unfortunately, only the  (+)(R)-thalidomide exhibited the required effect while (-)(S)-thalidomide is a teratogen.

This goes a long way to underscore the importance of separation of enantiomers in drug production.

Therefore, all the teratogenic effects observed when using the drug thalidomide was actually as a result of the presence of (-)(S)-thalidomide, the unwanted enantiomer.

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I need help with my chemistry homework please & thank u
lisov135 [29]

Answer:

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5 0
3 years ago
2 mg + 02–> 2Mg0 reaction type?
Serga [27]

Displacement reaction

5 0
3 years ago
Convert 22.4 kg/L to kg/mL
liberstina [14]
1 kg/L -------------- 0.001 kg/mL
22.4 kg/L --------- ??

22.4 x 0.001 / 1 => 0.0224 kg/mL
7 0
3 years ago
a boulder of shore is slowly broken apart by the force of the water it is a change or it is a example
natima [27]

Answer:

I think that this would be an example of erosion

6 0
2 years ago
Ammonia (NH3) is one of the most common chemicals produced in the united states. it is used to make fertilizer and other product
Greeley [361]

Answer:

a) N2 is the limiting reactant

b) <u>1215.9 grams NH3</u>

<u>c) 2283.6 grams H2</u>

Explanation:

Step 1: Data given

Mass of N2 = 1000 grams

Molar mass N2 = 28 g/mol

Mass of H2 = 2500 grams

Molar mass H2 = 2.02 g/mol

Step 2: The balanced equation

N2(g) +3H2(g) → 2NH3(g)

Step 3: Calculate moles N2

Moles N2 = mass N2 / molar mass N2

Moles N2 = 1000 grams / 28.0 g/mol

Moles N2 = 35.7 moles

Step 4: Calculate moles H2

Moles H2 = 2500 grams / 2.02 g/mol

Moles H2 = 1237.6 moles

Step 5: Calculate limiting reactant

For 1 mol N2 we need 3 moles H2 to produce 2 moles NH3

<u>N2 is the limiting reactant</u>. There will be consumed 35.7 moles.

H2 is in excess. There will react 3*35.7 = 107.1 moles

There will remain 1237.6 - 107.1= 1130.5 moles H2

This is 1130.5 * 2.2 = <u>2283.6 grams H2</u>

Step 6: Calculate moles NH3

For 1 mol N2 we need 3 moles H2 to produce 2 moles NH3

For  35.7 moles N2 we'll have 2*35.7 = 71.4 moles NH3

Step 7: Calculate mass NH3

Mass NH3 = moles NH3 * molar mass NH3

Mass NH3 = 71.4 moles * 17.03 g/mol

Mass NH3 = <u>1215.9 grams NH3</u>

7 0
3 years ago
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