1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
mixas84 [53]
3 years ago
13

Why chemically did the prescribing of thalidomide for morning sickness in pregnant women lead to tragic consequences, including

teratogenic effects?
Chemistry
1 answer:
Dominik [7]3 years ago
3 0

Answer:

See explanation

Explanation:

The drug thalidomide with molecular formula C13H10N2O4 was widely prescribed by doctors for morning sickness in pregnant women in the 1960s.

The drug was sold as a racemic mixture  (+)(R)-thalidomide and (-)(S)-thalidomide.

Unfortunately, only the  (+)(R)-thalidomide exhibited the required effect while (-)(S)-thalidomide is a teratogen.

This goes a long way to underscore the importance of separation of enantiomers in drug production.

Therefore, all the teratogenic effects observed when using the drug thalidomide was actually as a result of the presence of (-)(S)-thalidomide, the unwanted enantiomer.

You might be interested in
Mannoheptulose is a sugar found in avocados. If each C-C bond contains 76 kcal of energy and each C-H bond contains 91 kcal, how
nadya68 [22]

Answer:

Total Kcal energy produced in the catabolism of mannoheptulose = 1184 Kcal

Explanation:

The molecular formula of mannoheptulose is C₇H₁₄O₇.

The structure is as shown in the attachment below.

Number of C-C bonds present in mannoheptulose = 6

Number of C-H bonds present in mannoheptulose = 8

Since the each C-C bond contains 76 Kcal of energy,

Amount of energy present in six C-C bonds = 6 * 76 = 456 Kcal

Also, since each C-H bond contains 91 Kcal of energy;

amount of energy present in eight C-H bonds = 8 * 91 = 728 Kcal

Total Kcal energy produced in the catabolism of mannoheptulose = 456 + 728 = 1184 Kcal

6 0
3 years ago
Is solubility a physical change? Defend your answer.
fredd [130]

Answer:

yes

Explanation:

Solubility is an observation and no chemical reaction takes place. The composition of the compound/element is not changed.

- Hope that helped! Please let me know if you need further explanation.

3 0
3 years ago
Read 2 more answers
Newtons second law in your own words.
Misha Larkins [42]

Answer:

behavior of objects for which all existing forces are not balanced.

Explanation:

8 0
3 years ago
Read 2 more answers
Camilla believes that Earth's crust is evenly thick all around the globe, Maclaya thinks that Camilla is wrong, but doesatt know
xenn [34]

Answer:Macaya (floruit 1802), was a Kongolese-born Haitian revolutionary military leader. Macaya was one of the first black rebel leaders in Saint-Domingue to ally himself with the French Republican commissioners Sonthonax and Polverel. He helped to lead forces that recaptured Cap-Français on behalf of the French Republicans.

Macaya was born in west-central Africa, probably in the Kingdom of Kongo, and taken to the French colony of Saint-Domingue as a slave. After the outbreak of the 1791 slave rebellion in northern Saint-Domingue, Macaya became a lieutenant of an elderly rebel commander named Pierrot. Pierrot's rebel forces were based in the hills outside of Le Cap (Cap Francaise), near Bréda plantation by 1793.

Explanation:

7 0
2 years ago
How many atoms of nitrogen on the reactant side
Taya2010 [7]

Answer:

2 nitrogen atoms

Explanation:

6 0
3 years ago
Read 2 more answers
Other questions:
  • Why are atoms considered the smallest particles of an element?
    15·2 answers
  • Which of the following identifies the number and location of protons in a lithium atom
    13·1 answer
  • Does aluminum conduct electricity?
    9·1 answer
  • How many grams are in 4.65 mol of AI(NO2)3
    13·1 answer
  • What is the percent composition of potassium in KNO3
    5·2 answers
  • Consider a wooden chair and a balloon. What do these two
    15·1 answer
  • 1) Your nephew rides a kiddy train at the local carnival. The train, which has
    8·1 answer
  • Scientists discover two new elements, element A and element X, and are able to determine their atomic mass. Element A has an ato
    11·1 answer
  • Can someone help me with my chemistry homework please???
    14·1 answer
  • Thank uuuu so much!!!!!
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!