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Ad libitum [116K]
4 years ago
9

How does mg2+ block the effect of extracellular calcium on neurotransmitter release?

Chemistry
1 answer:
svetlana [45]4 years ago
5 0
<span>Magnesium is a strong anode than calcium. So, Mg will be oxidized into Mg2+. So instead of having Ca being the reducing agent, Mg will takes its place. That's how the "Blocking" occur.
</span><span>Without Ca2+, no neurotransmitter was released because the exocytosis of the synaptic vesicles is dependent upon Ca2+.
</span>So, when magnesium is added to the extracellular fluid it blocks the calcium channels and inhibits the release of <span>neurotransmitter.</span>
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