Question

1)The average lethal dose of Valium is 1.52 mg/kg of body weight. Estimate how many grams of Valium would be lethal for a 200.-lb woman. Show all your calculations. (1lb = 453.6 g)
2) A patient in hospital is receiving the antibiotic amoxcillin IV at the rate of 50. mL/h. The IV contains 1.5 g of the antibiotic in 1000. mL. (IV stands for intravenous). Calculate the mg/min of the drip. Show all your calculations

Answer 1

Answer:

1. 0.138g of valium would be lethel in the woman

2. 125mg/min is the drip of the patient

Explanation:

1. In a body, an amount of Valium > 1.52mg / kg of body weight would be lethal.

A person that weighs 200lb requires:

200lb × (453.6g / 1lb) × (1kg / 1000g) = 90.72kg (Weight of the woman in kg)

90.72kg × (1.52mg / kg) =

137.9mg ≡

0.138g of valium would be lethel in the woman

2. The IV contains 1.5g = 1500mg/mL.

If the patient is receiving 5.0mL/h, its rate in mg/h is:

5.0mL/h × (1500mg/mL) = 7500mg/h

Now as 1h = 60min:

7500mg/h × (1h / 60min) =

125mg/min is the drip of the patient