What is the net charge of the peptide arg-ala-phe-leu at ph 8?
1 answer:
The structure of this oligopeptide is attached:
It consists of arginine - alanine - phenylalanine and leucine
From the picture we can see that N terminus charge is +1
Also Arginine is considered as basic amino acid with charge +1
C terminus charge is -1
At pH = 8, the whose pKa are less than pH will be deprotonated and the net charge will be +1
So the net charge of this oligopeptide is +1 at pH = 8
It consists of arginine - alanine - phenylalanine and leucine
From the picture we can see that N terminus charge is +1
Also Arginine is considered as basic amino acid with charge +1
C terminus charge is -1
At pH = 8, the whose pKa are less than pH will be deprotonated and the net charge will be +1
So the net charge of this oligopeptide is +1 at pH = 8
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Answer:
(2R,3S)-2-ethoxy-3-methylpentane
and
(2S,3S)-2-ethoxy-3-methylpentane
Explanation:
For this case, we will have as nucleophile. Also, this compound is also in excess. So, we will have as solvent
a protic solvent. Therefore the Sn1 reaction would be favored.
The first step would be the carbocation formation followed by the attack of the nucleophile. In this case both isomers would be produced: R and S (see figure).
