Cyclic nucleotides cAMP and cGMP are part of almost all major cellular signaling pathways. Phosphodiesterases (PDEs) are enzymes that regulate the intracellular levels of cAMP and cGMP. Protein kinase A or cAMP-dependent protein kinase mediates most cAMP effects in the cell. Over the last 25 years, various components of this group of molecules have been involved in human diseases, both genetic and acquired. Lately, the PDEs attract more attention. The pharmacological exploitation of the PDE’s ability to regulate cGMP and cAMP, and through them, a variety of signaling pathways, has led to a number of new drugs for diverse applications from the treatment of erectile dysfunction to heart failure, asthma, and chronic obstructive pulmonary disease. We present the abstracts (available online) and selected articles from the proceedings of a meeting that took place at the National Institutes of Health (NIH), Bethesda, MD, June 8–10, 2011.
<span>Yes, each ATP molecule aids in moving 3 Na+ across the membrane.
so 150 </span>sodium ions are transported across the cell membrane when <span>50 ATP molecules are spent.</span>
Answer:
Option-1 (O²⁻) is the correct answer.
Explanation:
All given anions contains same charge. So, we can ignore the effect of charge on these anions.
As we know all given compounds belongs to same group (Group 6) in periodic table. And from top to bottom along the group the elements are placed as,
Oxygen O
Sulfur S
Selenium Se
Tellurium Te
Hence, moving from top to bottom along the group the number of shells increases. And with increase in number of shell the atomic or ionic radii increases. As Oxygen is present at the top of the group, therefore, it has the smallest radius due to less number of shells.
Atomic radius is the distance from the atom's nucleus to the outer edge of the electron cloud.
