Answer:
Four possible isomers (1–4) for the natural product essramycin. The structure of compound 1 was attributed to essramycin by 1H NMR, 13C NMR, HMBC, HRMS, and IR experiments.
Explanation:
Three synthetic routes were used to prepare all four compounds (Figure 2A). All three reactions utilize 2-(5-amino-4H-1,2,4-triazol-3-yl)-1-phenylethanone (5) as the precursor, whereas each uses different esters (6–8) to construct the pyrimidinone ring. Isomer 1 was prepared by reaction A, which used triazole 5 and ethyl acetoacetate (6) in acetic acid. This was the reaction used in syntheses of essramycin by the Cooper and Moody laboratories.3,4 Reaction B produced compound 2 (minor product) and compound 3 (major product), which were separated chromatographically. This reaction allowed reagent 5 to react with ethyl 3-ethoxy-2-butenoate (7) in the presence of sodium in methanol, under reflux for 24 h. Compound 4 was prepared by reaction C, which was obtained by reflux of 5 and methyl 2-butynoate (8) in n-butanol.
Answer:
The structures are shown in the figure.
Explanation:
The primary hydrogens are those which are attached to primary carbon.
Primary carbons are the carbons which are attached to only one carbon.
Primary carbons is bonded to three hydrogens.
In order to draw such structure we will draw structures which will have carbon with three hydrogens or no hydrogens (quaternary)
The structures are shown in the figure with clear marking.
Answer:
Explanation:
Hello.
In this case, taking into account that HCl has one molecule of hydrogen per mole of compound which weights 36.45 g/mol, we compute the number of molecules of hydrogen in hydrochloric acid by considering the given mass and the Avogadro's number:
Now, from the 180 g of water, we see two hydrogen molecules per molecule of water, thus, by also using the Avogadro's number we compute the molecules of hydrogen in water:
Thus, the total number of molecules turns out:
Regards.
Answer:
Explanation:
Given parameters:
Mass of aluminium oxide = 3.87g
Mass of water = 5.67g
Unknown:
Limiting reactant = ?
Solution:
The limiting reactant is the reactant in short supply in a chemical reaction. We need to first write the chemical equation and convert the masses given to the number of moles.
Using the number of moles, we can ascertain the limiting reactants;
Al₂O₃ + 3H₂O → 2Al(OH)₃
Number of moles;
Number of moles =
molar mass of Al₂O₃ = (2x27) + 3(16) = 102g/mole
number of moles = = 0.04mole
molar mass of H₂O = 2(1) + 16 = 18g/mole
number of moles = = 0.32mole
From the reaction equation;
1 mole of Al₂O₃ reacted with 3 moles of H₂O
0.04 mole of Al₂O₃ will react with 3 x 0.04 mole = 0.12 mole of H₂O
But we were given 0.32 mole of H₂O and this is in excess of amount required.
This shows that Al₂O₃ is the limiting reactant