hello your question lacks some parts below are the missing option
A.
hydrophobic interaction
B. nucleophilic attack
C. tautomerization
D. resonance
answer : Tautomerization ( C )
Explanation:
The large negative free energy of hydrolysis of Phosphoenolpyruvate is largely due to tautomerization of the enol pyruvate. tautomerism of enol takes place by transferring proton from in an intramolecular way.
one of the most common tautomerism is keto-enol which makes uses of either an acid or base as a catalyst
