Imatinib is a small molecule kinase inhibitor. The BCR-ABL kinase can phosphorylate a series of downstream substrates, leading to proliferation of mature granulocytes. Bcr-Abl kinase substrate is the tyrosine. The Protein Tyrosine Kinase activity is an important requirement for malignant transformation, and that it cannot be complemented by any downstream effector, though not all interactions of BCR-ABL with other proteins are phosphotyrosine dependent.
Answer:

Explanation:
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In this case, since the pH of the given metal is 10.15, we can compute the pOH as shown below:

Now, we compute the concentration of hydroxyl ions in solution:
![[OH^-]=10^{-pOH}=10^{-3.95}=1.41x10^{-4}M](https://tex.z-dn.net/?f=%5BOH%5E-%5D%3D10%5E%7B-pOH%7D%3D10%5E%7B-3.95%7D%3D1.41x10%5E%7B-4%7DM)
Now, since this hydroxide has the form MOH, we infer the concentration of OH- equals the concentration of M^+ at equilibrium, assuming the following ionization reaction:

Whose equilibrium expression is:
![Ksp=[M^+][OH^-]](https://tex.z-dn.net/?f=Ksp%3D%5BM%5E%2B%5D%5BOH%5E-%5D)
Therefore, the Ksp for the saturated solution turns out:

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<u>Given:</u>
Initial temperature, T1 = 20 C
Final temperature, T2 = 40 C
<u>To determine:</u>
The temperature change
<u>Explanation:</u>
Convert degree C to Kelvin
Temperature in Kelvin = degree C + 273
T1 = 20 + 273 = 293 K
T2 = 40 + 273 = 313 K
Incremental temperature change = T2 - T1 = 313-293 = 20 K
Ans: The temperature change in kelvin is 20 K
Answer:5
Explanation:(H3) is 3 (H3)2 is 5
Answer:
Hydrogen is an element
Explanation:
Hydrogen is an element with only hydrogen atoms, whereas air, carbon dioxide, and water are all made up of multiple elements with different types of atoms.