Atorvastatin is sold under the trade name Lipitor and is used for lowering cholesterol. Annual global sales of this compound exc
eed $13 billion. Assign a configuration to each chiral center in atorvastatin: In the boxes below, first input the numbers corresponding to the chiral centers in numerical order as a comma separated list (e.g., "1,3,4"). Then input the configurations of the chiral centers in the same order and format (e.g., "R,S,S"). chiral center(s): Configuration(s):
1 answer:
Answer:
Atorvastatin has two chiral centers. The question doesn't include the box where have to answer but I can show you in an image where are located and their configuration.
Explanation:
The first image shows the chemical structure of atorvastatin and their chiral centers identified as 1 and 2 respectively.
The second image shows the Fischer projections corresponding to every chiral carbon 1 and 2. I wrote R so suggest that there are more carbon atoms forward but not only corresponds to carbon atoms.
You can see that the chiral carbon 1 has R configuration due to the direction from the main substituent to the second follow the clockwise.
The chiral carbon 2 has S configuration due to the direction from the main substituent to the second one go anticlockwise.
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Answer:
197mL of 0,506M HCl
Explanation:
The reaction of HCl + BaCO₃ is:
BaCO₃(s) + 2HCl → BaCl₂(aq) + CO₂ + H₂O.
The moles of BaCO₃ in 9,85 g are:
9,85 g of BaCO₃ × = <em>0,0499 moles of BaCO₃</em>
As 1 mol of BaCO₃ reacts with two moles of HCl, for a complete reaction of BaCO₃ to dissolve this compound in water you need:
0,0499 moles of BaCO₃ × =<em> 0,0998 moles of HCl</em>
If you have a 0,506M HCl, you need to add:
0,0998 moles of HCl× = 0,197 L ≡ 197mL
I hope it helps!
The energy of the reactant has been higher than the energy of the product, Thus, the reaction has been an exothermic reaction.
Bond energy has been defined as the chemical energy possessed by the bonds in the chemical structure. The energy has been conserved in the chemical reaction.
<h3>Is the reaction endothermic or exothermic?</h3>In the reaction in which bond energy of the reactant has been higher than the product, it has been an exothermic reaction.
In the reaction in which the bond energy of the product is higher than the reactant, it has been an endothermic reaction.
In the given reaction
The bond energies of reactant has been:
- H-C bond = 413 kJ/mol
- C-C bond = 347 kJ/mol
The total bond energy of the reactant has been:
The total bond energy of the reactant has been 2,825 kJ/mol.
The bond energies of product has been:
- H-C = 413 kJ/mol
- C=C = 614 kJ/mol
- H-H = 432 kJ/mol
The total bond energy of the product has been:
The total bond energy of the product has been 2,698 kJ/mol.
The energy of the reactant has been higher than the energy of the product, Thus, the reaction has been an exothermic reaction, as energy can neither be created nor be destroyed. It has been conserved in the chemical reaction.
Learn more about exothermic reaction, here: