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Mashutka [201]
3 years ago
6

Atorvastatin is sold under the trade name Lipitor and is used for lowering cholesterol. Annual global sales of this compound exc

eed $13 billion. Assign a configuration to each chiral center in atorvastatin: In the boxes below, first input the numbers corresponding to the chiral centers in numerical order as a comma separated list (e.g., "1,3,4"). Then input the configurations of the chiral centers in the same order and format (e.g., "R,S,S"). chiral center(s): Configuration(s):

Chemistry
1 answer:
kotegsom [21]3 years ago
4 0

Answer:

Atorvastatin has two chiral centers. The question doesn't include the box where have to answer but I can show you in an image where are located and their configuration.

Explanation:

The first image shows the chemical structure of atorvastatin and their chiral centers identified as 1 and 2 respectively.

The second image shows the Fischer projections corresponding to every chiral carbon 1 and 2. I wrote R so suggest that there are more carbon atoms forward but not only corresponds to carbon atoms.

You can see that the chiral carbon 1 has R configuration due to the direction from the main substituent to the second follow the clockwise.

The chiral carbon 2 has S configuration due to the direction from the main substituent to the second one go anticlockwise.

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This addition reaction yields 3-BromoPentane and 2-BromoPentane.

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3 years ago
What describes the solvent in any solution
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Solvent is more than a solute. Like salt water. Water is the solvent and salt will be the solute
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4 0
2 years ago
A saturated solution is made by dissolving 0.327 g of a polypeptide (a substance formed by joining together in a chainlike fashi
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Answer: The approximate molecular mass of the polypeptide is 856 g/mol

Explanation:

To calculate the concentration of solute, we use the equation for osmotic pressure, which is:

\pi=iMRT

Or,

\pi=i\times \frac{\text{Mass of solute}}{\text{Molar mass of solute}\times \text{Volume of solution in L)}}\times RT

where,

\pi = osmotic pressure of the solution = 4.19 torr

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Mass of solute (polypeptide) = 0.327 g

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T = temperature of the solution = 26^oC=[273+26]K=299K

Putting values in above equation, we get:

4.19torr=1\times \frac{0.327}{\text{Molar mass of solute}\times 1.70}\times 62.364\text{ L.mmHg }mol^{-1}K^{-1}\times 299K\\\\\text{molar mass of solute}=856g/mol

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8 0
3 years ago
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