Your question looks a bit incomplete as you have the same contents in options a) and d). According to your list, I can't see the correct answer, but I can give you one.The difference between the potential energy of the products of the potential energy of the reactants is equal to the enthalpy of the reaction.
Isotopes are atoms of the same element that have different numbers of neutrons in their nuclei. Everything else about them is the same.(If you want more explanation tell me).