Answer: The classical complement pathway for complement activation is initiated by antigen-antibody complexes with the antibody isotypes IgG and IgM.
Explanation: The classical complement pathway typically requires antigen-antibody complexes (immune complexes) for activation (specific immune response), whereas the alternative pathway can be activated by C3 hydrolysis, foreign material, pathogens, or damaged cells.
After activation, a series of proteins are recruited to generate C3 convertase, which cleaves the C3 protein. The C3b component of the cleaved C3 binds to C3 convertase to generate C5 convertase, which cleaves the C5 protein. The cleaved products attract phagocytes to the site of infection and tags target cells for elimination by phagocytosis. In addition, the C5 convertase initiates the terminal phase of the complement system, leading to make appear the membrane attack complex. The membrane attack complex creates a pore on the target cell's membrane, inducing cell lysis and death.
Answer:
Work, W = 846.72 Joules
Explanation:
Given that,
Mass of the watermelon, m = 4.8 kg
It is dropped from rest from the roof of 18 m building. We need to find the work done by the gravity on the watermelon from the roof to the ground. It is same as gravitational potential energy i.e.
W = mgh
W = 846.72 Joules
So, the work done by the gravity on the watermelon is 846.72 Joules. Hence, this is the required solution.
Answer:
The driving force for (a) heat transfer is temperature difference. (b) electric current is voltage difference. (c) fluid flow is pressure or hydraulic head difference.
Explanation: (a) The driving force for heat transfer is temperature difference. Heat transfer between two mediums is possible only if the two mediums are at different temperature, the higher the temperature, the higher the heat transfer.
(b) The driving force for electric current is voltage difference. Voltage difference is defined as the potential difference in charge between two points in electrical field. For electric current to occur,the voltage must be high.
(c) The driving force for fluid flow is pressure difference or hydraulic head difference. For fluid to move upward,it requires energy.
If you decrease the pressure of a fixed amount of gas, its volume will increase.
