Answer:
Here's what I get
Explanation:
You may have done a Williamson synthesis of guaifenesin by reacting guaiacol with 3-chloropropane-1,2-diol.
A. Mechanism
Step 1
NaOH converts guaiacol into a phenoxide ion.
Step 2
The phenoxide acts as the nucleophile in an SN2 reaction to displace the Cl from the alkyl halide.
B. Improve the yield
You probably carried out the reaction in ethanol solution — a polar protic solvent.
You might try doing the reaction in a polar aprotic solvent— perhaps DMSO.
A polar aprotic solvent does not hydrogen bond to nucleophiles, so they become stronger.
C. Another method of ether synthesis —dehydration of alcohols
Sulfuric acid catalyzes the conversion of primary alcohols to ethers.
This is also a nucleophilic displacement reaction.
Protonation of the OH converts it into a better leaving group.
Attack by a second molecule of alcohol forms the protonated ether.
A molecule of water then removes the proton.
Yes because molecules is solid
The volume of the 0.279 M Ca(OH)₂ solution required to neutralize 24.5 mL of 0.390 M H₃PO₄ is 51.4 mL
<h3>Balanced equation </h3>
2H₃PO₄ + 3Ca(OH)₂ —> Ca₃(PO₄)₂ + 6H₂O
From the balanced equation above,
- The mole ratio of the acid, H₃PO₄ (nA) = 2
- The mole ratio of the base, Ca(OH)₂ (nB) = 3
<h3>How to determine the volume of Ca(OH)₂ </h3>
- Molarity of acid, H₃PO₄ (Ma) = 0.390 M
- Volume of acid, H₃PO₄ (Va) = 24.5 mL
- Molarity of base, Ca(OH)₂ (Mb) = 0.279 M
- Volume of base, Ca(OH)₂ (Vb) =?
MaVa / MbVb = nA / nB
(0.39 × 24.5) / (0.279 × Vb) = 2/3
9.555 / (0.279 × Vb) = 2/3
Cross multiply
2 × 0.279 × Vb = 9.555 × 3
0.558 × Vb = 28.665
Divide both side by 0.558
Vb = 28.665 / 0.558
Vb = 51.4 mL
Thus, the volume of the Ca(OH)₂ solution needed is 51.4 mL
Learn more about titration:
brainly.com/question/14356286
Kepler did not study the speed of the planets, rather, he studied how the planets move in the solar system. He proposed three laws. As a summary, he described that the planets move around the sun in the shape of an ellipse (orbit), and the Sun being one of the foci. Then, he proposed the period for the planet to complete one revolution around the Sun.
On the other hand, Newton studied the forces acting on the planet (or any object in space) that explain how the planets move around the solar system as described by Kepler. Also, Kepler's observations only apply to planets and not the moons or satellites. Thus, Kepler only made laws from observations, while Newton based it from underlying principles that led him to mathematical equations such as the law of universal gravitation.
