The scenario that supports the "one gene-one enzyme" hypothesis of metabolic disease causation is Phenylketonuria (PKU). This disease (PKU) is caused by the failure to produce a functional variant of an enzyme.
Phenylketonuria (PKU) is a metabolic inherited disorder associated with a decreased metabolism of the amino acid phenylalanine.
PKU is caused by a mutation in the gene responsible for encoding a key enzyme needed to break down phenylalanine.
Untreated PKU may lead to diverse health problems which include brain damage, intellectual disability, seizures, mental disorders, etc.
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1.5 ms⁻²
Explanation:
We understand that Force is also given as mass * acceleration;
F = Ma
If force is 6N and the mass is 4kg of the object, the a can be evaluated as follows;
6 = 4a
6/4 = a
1.5 = a
= 1.5m/s²
6.9 Sleps 1. (8)(13) = 15 2. 104/15 = 15/15 3. 6.93333333 4. 6.9 Sleps