During translation, the new polypeptides are often directed to specific parts of the cell by the presence or absence of short se
quences of amino acids called signal sequences. Which peptides would you expect to find in the polypeptide that will eventually fold to become an ion channel protein? Select all that apply.
a. an internal signal peptide
b. an amino-terminal signal
c. peptide a signal-anchor
d. peptide no signal peptide
A polypeptide that will eventually fold to become an ion channel protein, it means a kind of integral membrane protein, has an amino terminal signal that indicates its delivery to endoplasmic reticulum (ER) and then to the membrane. This type of signal usually consist in a nucleus of 6 to 12 aminoacids and one or more basic aminoacids. Once the polypeptide enters the ER, this signal is removed.
