Stark contrast to paths on energy surfaces or even mechanistic reactions, rule-based and inductive computational approaches to reaction prediction mostly consider only overall transformations. Overall transformations are general molecular graph rearrangements reflecting only the net change of several successive mechanistic reactions. For example, Figure 1 shows the overall transformation of an alkene interacting with hydrobromic acid to yield the alkyl bromide along with the two elementary reactions which compose the transformation.
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Explanation:
Answer:
1911
Explanation:
"In 1911, he was the first to discover that atoms have a small charged nucleus surrounded by largely empty space, and are circled by tiny electrons, which became known as the Rutherford model (or planetary model) of the atom."