Construct a three-step synthesis of 1,2-epoxycyclopentane from cyclopentanol by dragging the appropriate formulas into the bins.

Question

2 years ago

9

Note that each bin will hold only one item, and not all of the given reagents or structures will be used.

1 answer:

vladimir2022 [97] · Answer 1 · 2022-07-19T01:45:00+03:00

Answer:

(1) Bromination, (2) E2 elimination and (3) epoxidation

Explanation:

In the first step, -OH group in cyclopentanol is replaced by more facile leaving group Br by treating cyclopentanol with $PBr_{3}$

In the second step, E2 elimination in presence of strong base e.g. NaOEt/EtOH produce cyclopentene

In the third step, treatment of cyclopentene with mCPBA produces 1,2-epoxycyclopentane