Before you start working on any motion problem, YOU decide which direction you're going to call 'positive'. Everybody almost always calls UP positive, and the acceleration of gravity points down, so it winds up negative. But you could just as well call DOWN the positive direction. Then, the cannonball is fired with a negative vertical speed, and the acceleration of gravity eventually robs all of its negative speed, and makes it start falling in the positive direction. The whole thing is your choice.
An epidemiologist is a doctor who counteracts mass infections (epidemics, pandemics), organizes the treatment and prevention of the spread of epidemics.
Muscle cells have to use a lot of energy and the Mitochondria is known as the "power house" of the cell... I would say the number of mitochondria needed is increased because more power and energy is being used in that cell than a normal one (idk if this helps or if that's the answer you were looking for)
