Question

The following steps refer to various stages in transmission at a chemical synapse. 1. Neurotransmitter binds with receptors associated with the postsynaptic membrane. 2. Calcium ions rush into neuron's cytoplasm. 3. An action potential depolarizes the membrane of the presynaptic axon terminal. 4. The ligand-gated ion channels open. 5. The synaptic vesicles release neurotransmitter into the synaptic cleft. Which sequence of events is correct?

Answer 1

Answer:

3,2,5,1,4

Explanation:

A chemical synapse begins when an (3)action potential reaches the axon terminal depolarizing the membrane leading to the opening of the voltage-gated Na+ channels, this Na+ ions will then depolarize the presynaptic membrane, opening the voltage-gated Ca2+ channels. (2)Calcium ions then will initiate a cascade entering the neuron that will lead to the fusion of synaptic vesicles with the presynaptic membrane (5)causing the releasing of neurotransmitters into the synaptic cleft. (1)These neurotransmitter will diffuse across the synaptic place in order to bind to the receptors on the postsynaptic membrane, (4)particulary into the ligand-gated channels, opening them.

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