The epidermis, the top layer
The dermis, middle layer
The hypodermis, bottom layer
There you go!
The answer to this question would be: resistance
When a patient developing a resistance to a certain drug, the same amount of doses will not exert the same effect as before. The effect will be lower, thus the doctor will need to increase the dose to increase the effect
In order to determine the mass of a substance given the volume, we require the density. The density of iron is 7.87 grams/cm³
Now,
Density = mass / volume
Mass = density * volume
Mass = 7.87 * 4.6
36.2 grams of iron are present in the cube
It’s oxidation number is +6
