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iren [92.7K]
4 years ago
6

A deficiency in thiamine (TPP) will directly decrease the activity of which of the following enzymes? a. Pyruvate carboxylase b.

Glucose 6-phosphate dehydrogenase c. Aldolase Bd. Transketolase
Chemistry
1 answer:
Blababa [14]4 years ago
3 0

Answer:

d. Transketolase

Explanation:

Transketolase utilize thiamine diphosphate (ThDP) as cofactor has reduced activity during the thiamine deficiency and results in the tissue damage. <u>The levels of steady-state mRNA of transketolase in human lymphoblasts, fibroblasts and neuroblastoma cells are found to be lower in the thiamine-deficient cultures.  </u>

Thus, deficiency in TPP directly decrease the activity of enzyme, transketolase.

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