Answer:
Four possible isomers (1–4) for the natural product essramycin. The structure of compound 1 was attributed to essramycin by 1H NMR, 13C NMR, HMBC, HRMS, and IR experiments.
Explanation:
Three synthetic routes were used to prepare all four compounds (Figure 2A). All three reactions utilize 2-(5-amino-4H-1,2,4-triazol-3-yl)-1-phenylethanone (5) as the precursor, whereas each uses different esters (6–8) to construct the pyrimidinone ring. Isomer 1 was prepared by reaction A, which used triazole 5 and ethyl acetoacetate (6) in acetic acid. This was the reaction used in syntheses of essramycin by the Cooper and Moody laboratories.3,4 Reaction B produced compound 2 (minor product) and compound 3 (major product), which were separated chromatographically. This reaction allowed reagent 5 to react with ethyl 3-ethoxy-2-butenoate (7) in the presence of sodium in methanol, under reflux for 24 h. Compound 4 was prepared by reaction C, which was obtained by reflux of 5 and methyl 2-butynoate (8) in n-butanol.
Answer:
Explained
Explanation:
The bond angle between the Si-O-Si is 145° .But this can also vary between 100° and 170°, It is because of which the changes in properties is happening. Bond angles can affect the hybridization, lone pair repulsion and electronegativity.
Thus , Space shuttle tiles, sandstone, and the glass in quartz have different properties and are used according to their property.
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air. ... Carbon monoxide consists of one carbon atom and one oxygen atom, connected by a triple bond that consists of two covalent bonds as well as one dative covalent bond.
I think it's probably not right.