<u>Oxidative phosphorylation </u>occurs during the electron transport chain which is the final phase of cellular respiration. It depends on the hydrogen ion concentration gradient generated and is maintained by the electron transport chain.
<u>The oxidative phosphorylation acquires energy of high-energy electrons to synthesize ATP. During this process ADP is the major regulator of oxygen consumption.</u>
The regulation by ADP is referred to as the acceptor or respiratory control.
The level of ADP is the most important factor in the determination of the rate of Oxidative Phosphorylation.
The rate of oxygen utilization by the Mitochondria is increased when ADP is added and usually returns to its initial level when the added ADP has being converted to ATP.
